27 August 2026 Ahmedabad : At forty-nine, changes in the menstrual cycle may not seem unusual. As women approach menopause, their periods can become irregular, and abnormal bleeding may sometimes be attributed to hormonal changes.
But when abnormal uterine bleeding keeps happening, it is important not to assume that it is simply a normal part of perimenopause.
For Mrs Masum Gajjar (Name Changed), a 49-year-old woman going through perimenopause, the abnormal bleeding did not stop. She decided to seek medical attention, and further evaluation revealed early-stage endometrial cancer.
Her diagnosis marked the beginning of a treatment journey that was planned around not only the stage of her cancer, but also the unique biology of her tumour.
At KD Cancer Centre, Dr Somesh Chandra and his team meticulously planned Mrs Masum Gajjar’s treatment, emphasising personalised and evidence-based cancer care.
She underwent a robotic hysterectomy with sentinel lymph node biopsy. This minimally invasive approach allowed the cancer to be treated surgically while also enabling the team to assess the lymph nodes for any evidence of spread.
But to understand her cancer completely, the team needed to look beyond surgery.
Let’s understand what made her endometrial cancer different. Cancer care is increasingly becoming more personalised. While knowing the type and stage of cancer is important, understanding molecular characteristics of a tumour can provide additional information to help doctors make informed treatment decisions.
Molecular testing of Mrs Masum Gajjar’s tumour identified a POLE mutation. POLE-mutated endometrial cancers have distinct biological characteristics and, in appropriately selected patients, may be associated with a favourable prognosis.
Considering her complete clinical, pathological and molecular findings, Dr Somesh Chandra and his team determined that she did not require adjuvant treatment after surgery.
This meant that she could avoid the potential side effects of additional treatment and continue with appropriate follow-up and regular monitoring.
Today, Mrs Masum is doing well, with no evidence of disease recurrence.
Her story is an example of how personalised cancer care can make a meaningful difference.
Cancer treatment is not always about giving more treatment. Sometimes, it is about understanding the disease more precisely and recognising when additional treatment may not be necessary.
By combining minimally invasive surgery, detailed pathological assessment and molecular testing, the team at KD Cancer Centre was able to develop a treatment approach tailored to the specific characteristics of Mrs Masum Gajjar’s cancer.
Her Story Carries a Message for Every Woman
Abnormal uterine bleeding should not simply be dismissed as a normal part of perimenopause.
If bleeding is persistent, unusual or heavier than expected, it is important to seek medical evaluation. Detecting endometrial cancer at an early stage can provide an opportunity for timely treatment and appropriate care.
